id | GO:0000060   Detailed information |
---|---|
  name | protein import into nucleus, translocation |
  namespace | biological_process |
  def | "A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope." [GOC:curators, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:14570049, PMID:9126736] |
  comment | Note that 'vectorial' is used in the definition in the mathematical and physical sense of pertaining to 'a quantity having direction as well as magnitude, especially as determining the position of one point in space relative to another. Note that 'translocation' is sometimes used in the literature to refer to the entire process of protein import into the nucleus, but in GO refers specifically to the step in which a cargo-carrier protein complex moves through the nuclear pore complex. |
  synonym | "protein import into cell nucleus, translocation" EXACT [] |
  synonym | "protein translocation during protein import into nucleus" EXACT [] |
  synonym | "protein translocation during protein transport from cytoplasm to nucleus" EXACT [] |
  synonym | "protein translocation during protein-nucleus import" EXACT [] |
  synonym | "protein transport from cytoplasm to nucleus, translocation" EXACT [] |
  synonym | "protein-nucleus import, translocation" EXACT [] |
  is_a | GO:0006886 ! intracellular protein transport |
  relationship | part_of GO:0006606 ! protein import into nucleus |
  DPGLEAN03525
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  DPGLEAN06594
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