id | GO:0035004   Detailed information |
---|---|
  name | phosphatidylinositol 3-kinase activity |
  namespace | molecular_function |
  def | "Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring to generate the 3-phosphoinositides: phosphatidylinositol-3-phosphate [PI(3)P], phosphatidylinositol-3,4-bisphosphate [PI(3,4)P2] and phosphatidylinositol-3,4,5-trisphosphate [PI(3,4,5)P3]." [GOC:bf, PMID:10209156, PMID:9255069] |
  synonym | "phosphoinositide 3-kinase activity" EXACT [GOC:curators] |
  xref | EC:2.7.1.- |
  xref | Wikipedia:Phosphoinositide_3-kinase |
  is_a | GO:0001727 ! lipid kinase activity |
  is_a | GO:0004428 ! inositol or phosphatidylinositol kinase activity |
  is_a | GO:0016773 ! phosphotransferase activity, alcohol group as acceptor |
  relationship | part_of GO:0046854 ! phosphatidylinositol phosphorylation |
  DPGLEAN03320
  DPGLEAN03321
  DPGLEAN04749
  DPGLEAN10709
  DPGLEAN10710