id | GO:0004108   Detailed information |
---|---|
  name | citrate (Si)-synthase activity |
  namespace | molecular_function |
  def | "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group." [EC:2.3.3.1, ISBN:0121227073] |
  comment | Note that this function was formerly EC:4.1.3.7. |
  subset | gosubset_prok |
  synonym | "(R)-citric synthase activity" EXACT [EC:2.3.3.1] |
  synonym | "acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming]" RELATED [EC:2.3.3.1] |
  synonym | "citrate condensing enzyme activity" EXACT [EC:2.3.3.1] |
  synonym | "citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity" EXACT [EC:2.3.3.1] |
  synonym | "citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA)" EXACT [EC:2.3.3.1] |
  synonym | "citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA]" RELATED [EC:2.3.3.1] |
  synonym | "citrate oxaloacetate-lyase, CoA-acetylating activity" EXACT [EC:2.3.3.1] |
  synonym | "citrate synthase activity" BROAD [EC:2.3.3.1] |
  synonym | "citrate synthetase activity" EXACT [EC:2.3.3.1] |
  synonym | "citric synthase activity" EXACT [EC:2.3.3.1] |
  synonym | "citric-condensing enzyme activity" EXACT [EC:2.3.3.1] |
  synonym | "citrogenase activity" EXACT [EC:2.3.3.1] |
  synonym | "condensing enzyme activity" BROAD [EC:2.3.3.1] |
  synonym | "oxalacetic transacetase activity" EXACT [EC:2.3.3.1] |
  synonym | "oxaloacetate transacetase activity" EXACT [EC:2.3.3.1] |
  xref | EC:2.3.3.1 |
  xref | MetaCyc:CITSYN-RXN |
  xref | Reactome:8157 "citrate (Si)-synthase activity" |
  is_a | GO:0046912 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer |
  DPGLEAN02560