| New model in OGS2.0 | DPOGS201001 |
|---|---|
| Genomic Position | scaffold601:- 27801-46704 |
| See gene structure | |
| CDS Length | 1824 |
| Paired RNAseq reads | 1243 |
| Single RNAseq reads | 3233 |
| Migratory profiles | Query via corresponding ESTs |
| Best Bmobyx hit | BGIBMGA009071 (2e-64) |
| Best Drosophila hit | pten, isoform E (5e-73) |
| Best Human hit | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (7e-78) |
| Best NR hit (blastp) | phosphatase and tensin-like [Apis mellifera] (7e-107) |
| Best NR hit (blastx) | phosphatase and tensin-like C [Apis mellifera] (6e-105) |
| GeneOntology terms | GO:0000287 magnesium ion binding GO:0001525 angiogenesis GO:0002902 regulation of B cell apoptosis GO:0004438 phosphatidylinositol-3-phosphatase activity GO:0004722 protein serine/threonine phosphatase activity GO:0004725 protein tyrosine phosphatase activity GO:0005515 protein binding GO:0006470 protein amino acid dephosphorylation GO:0007417 central nervous system development GO:0010975 regulation of neuron projection development GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity GO:0030165 PDZ domain binding GO:0031647 regulation of protein stability GO:0033032 regulation of myeloid cell apoptosis GO:0043066 negative regulation of apoptosis GO:0043542 endothelial cell migration GO:0046855 inositol phosphate dephosphorylation GO:0046856 phosphoinositide dephosphorylation GO:0048738 cardiac muscle tissue development GO:0050680 negative regulation of epithelial cell proliferation GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity GO:0051726 regulation of cell cycle GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity GO:0051895 negative regulation of focal adhesion assembly GO:0051898 negative regulation of protein kinase B signaling cascade GO:0060736 prostate gland growth |
| InterPro families | IPR014019 Phosphatase tensin type IPR014020 Tensin phosphatase, C2 domain IPR008973 C2 calcium/lipid-binding domain, CaLB IPR000340 Dual specificity phosphatase, catalytic domain IPR003595 Protein-tyrosine phosphatase, catalytic IPR016130 Protein-tyrosine phosphatase, active site |
| Orthology group | MCL15613 |
Nucleotide sequence:
ATGACCAACCCTATCAAGGGCATCGTGAGCAAACGCCGAAAACGATACGTGAAGGACGGC
TTTAATTTAGACTTAGCATATATAACGGACAGGTTAATAGCTATGGGCTTCCCCGCCGAG
AAGCTGGAGGGTGTGTACAGGAACCACATAGATGAAGTGTACCGCTTCCTGGAACAGAAG
CACAAGGACCACTACATGATATACAACCTGTGCGCCGAGAGAGAGTACGACTACACCAAG
TTCAACAAGAGGGTGCAAGTGTTCGCGTTCAAGGACCACGAGCCGCCGAAGATCGGTCAG
ATCCAGCCGTTCTGTGAGGACGTTCACAACTGGCTCAGCAAGGACCCTCGGAACGTGGCC
GCCGTGCACTGCAAGGCTGGCAAAGGAAGAACCGGTACAATGGTGTGCTGCTACCTGCTG
TACAGCGGACAGAAGACCACGGCGGATGAGGCTCTTAAATACTATGGGAACAAACGCACA
CACGACGAGAAAGGTGTTACGATCCCGTCCCAGCGACGCTACGTGGAGTACTACGCGGCG
CTGGTCCGAGGAGGGCTCTCGTACCGCGCCACCAGGGTGCACGTCCGGGAGCTCCTCATG
TACCCTCCGCCGGCCTTCAACGGCTCGCAGTGTACCCTGCAGCTGACGGTCACGCAGGCT
GACCCCTTCCACAAGACGTCGCTGGGCAGCCACGAGGTGCGCCGCCACGAGTCGGTGGCG
CGGGTGGTGGCGACGGCGTGCGCTCCGCTGGCCGGGGACGTGCGGGTGGACGTGTACTGC
AAGCCCAAGATGAAGATGAGGAAGGAGAGGCTGTTCCACTTCTGGTTCAACACGTACTTC
GTCACCGCTGGCGTCGGAGCCGCCAACGTGCCCGCGCCCATCGACAGTCAAAATCAAGAA
ACATTCAAGTTGACGCTGGACAAGTGGCAGCTGGACGACGCGCACAAAGACAAGCAACAC
AAAATGTACAGCGCCGACTTTAAGGTGGAGCTGATAGTTCACAAGCTGCCCGAGTCGTCG
ACGTTCAGCGTTCCCCGCGGGTCCTCTCCGGCCAGCTCCTCCTCGGACCCGGACACGGAA
CACGAGCAGGAGTGGGACTCCGGTGAGACAGACTACACTACGGACAAATATCTCCAGACA
GATCCCGAGATAGATCCCGAGATAGACCGCGGGATATCCGACGCGGCCGACTCCGACAGG
CAGCTTCACACCAGTCACCAGTACCATCGCCAGCGGGAATGCGACGCTCTACCGGGGTCG
AACCCGTTCTATCCCCGGAGCGATCCGTTCGCTCCCTCCGACCTCCCTCCCCGGTTACGT
CCCGGGCCCGACCCGCAGCACTCCCCTCCCTACCGCTATCTGTCAAACGTGCCCGAATAT
CCCGAACACTTCCCTCGAGACTGTACGAGGGTGGATCGCCCGCCCCCGACACACACCACC
CACCCTCCCGAGACGAACACCAACGGTGACGAGGACCTCCTGTACACCGACACCGAGCCG
GTCATGTTCGGCGGACACAAACTAGCAGACTATCGCTTAGAGAAATTGCCGGAGTACACT
CACAGTGGCTACTACGACGACAGAAATAACTTCAACGTACCGATGGCGCGGTACGACGTG
TGTCCCGGGGACGAGTACCCGGCGGGGGAGGACGCCGACACTATGGAGTACCGCGGGGAC
GACGCCAAACAATACGATAGGAATAAGAAGTGCAAGGACCCTCTCACCAAGCCGCGTCTG
TCGCTGGGGGACATGAGGGCCTCGTGGAGAGAGTTCAGCGGCAAGTTCGGCGAGAACAGG
AAAAAGAAGAATAGGGACGACTGA
Protein sequence:
MTNPIKGIVSKRRKRYVKDGFNLDLAYITDRLIAMGFPAEKLEGVYRNHIDEVYRFLEQK
HKDHYMIYNLCAEREYDYTKFNKRVQVFAFKDHEPPKIGQIQPFCEDVHNWLSKDPRNVA
AVHCKAGKGRTGTMVCCYLLYSGQKTTADEALKYYGNKRTHDEKGVTIPSQRRYVEYYAA
LVRGGLSYRATRVHVRELLMYPPPAFNGSQCTLQLTVTQADPFHKTSLGSHEVRRHESVA
RVVATACAPLAGDVRVDVYCKPKMKMRKERLFHFWFNTYFVTAGVGAANVPAPIDSQNQE
TFKLTLDKWQLDDAHKDKQHKMYSADFKVELIVHKLPESSTFSVPRGSSPASSSSDPDTE
HEQEWDSGETDYTTDKYLQTDPEIDPEIDRGISDAADSDRQLHTSHQYHRQRECDALPGS
NPFYPRSDPFAPSDLPPRLRPGPDPQHSPPYRYLSNVPEYPEHFPRDCTRVDRPPPTHTT
HPPETNTNGDEDLLYTDTEPVMFGGHKLADYRLEKLPEYTHSGYYDDRNNFNVPMARYDV
CPGDEYPAGEDADTMEYRGDDAKQYDRNKKCKDPLTKPRLSLGDMRASWREFSGKFGENR
KKKNRDD