| New model in OGS2.0 | DPOGS211051 |
|---|---|
| Genomic Position | scaffold40:+ 223281-229965 |
| See gene structure | |
| CDS Length | 3327 |
| Paired RNAseq reads | 288 |
| Single RNAseq reads | 684 |
| Migratory profiles | Query via corresponding ESTs |
| Best Bmobyx hit | BGIBMGA003802 (6e-98) |
| Best Drosophila hit | Alk (2e-36) |
| Best Human hit | insulin receptor isoform Short preproprotein (6e-40) |
| Best NR hit (blastp) | venus kinase receptor [Tribolium castaneum] (6e-67) |
| Best NR hit (blastx) | venus kinase receptor [Anopheles gambiae] (9e-57) |
| GeneOntology terms | GO:0051425 PTB domain binding GO:0043560 insulin receptor substrate binding GO:0043548 phosphoinositide 3-kinase binding GO:0051290 protein heterotetramerization GO:0005515 protein binding GO:0010629 negative regulation of gene expression GO:0019903 protein phosphatase binding GO:0032410 negative regulation of transporter activity GO:0045471 response to ethanol GO:0005009 insulin receptor activity GO:0019087 transformation of host cell by virus GO:0030335 positive regulation of cell migration GO:0031994 insulin-like growth factor I binding GO:0005159 insulin-like growth factor receptor binding GO:0048639 positive regulation of developmental growth GO:0005887 integral to plasma membrane GO:0051897 positive regulation of protein kinase B signaling cascade GO:0043410 positive regulation of MAPKKK cascade GO:0046777 protein amino acid autophosphorylation GO:0030238 male sex determination GO:0045740 positive regulation of DNA replication GO:0003007 heart morphogenesis GO:0008284 positive regulation of cell proliferation GO:0031017 exocrine pancreas development GO:0033574 response to testosterone stimulus GO:0031995 insulin-like growth factor II binding GO:0045821 positive regulation of glycolysis GO:0005525 GTP binding GO:0018108 peptidyl-tyrosine phosphorylation GO:0004713 protein tyrosine kinase activity GO:0032148 activation of protein kinase B activity GO:0043559 insulin binding GO:0008286 insulin receptor signaling pathway GO:0001933 negative regulation of protein amino acid phosphorylation GO:0005625 soluble fraction GO:0032355 response to estradiol stimulus GO:0034612 response to tumor necrosis factor GO:0005792 microsome GO:0032869 cellular response to insulin stimulus GO:0005886 plasma membrane GO:0010008 endosome membrane GO:0005634 nucleus GO:0010042 response to manganese ion GO:0043423 3-phosphoinositide-dependent protein kinase binding GO:0051789 response to protein stimulus GO:0016020 membrane GO:0060267 positive regulation of respiratory burst GO:0045429 positive regulation of nitric oxide biosynthetic process GO:0046326 positive regulation of glucose import GO:0042169 SH2 domain binding GO:0005768 endosome GO:0005829 cytosol GO:0032403 protein complex binding GO:0045444 fat cell differentiation GO:0042593 glucose homeostasis GO:0045840 positive regulation of mitosis GO:0005975 carbohydrate metabolic process GO:0046872 metal ion binding GO:0010310 regulation of hydrogen peroxide metabolic process GO:0010560 positive regulation of glycoprotein biosynthetic process GO:0031667 response to nutrient levels GO:0045202 synapse GO:0005524 ATP binding GO:0005901 caveola GO:0045995 regulation of embryonic development GO:0007186 G-protein coupled receptor protein signaling pathway GO:0005899 insulin receptor complex GO:0000166 nucleotide binding GO:0004872 receptor activity GO:0016740 transferase activity GO:0009749 response to glucose stimulus GO:0014823 response to activity GO:0031405 lipoic acid binding GO:0033280 response to vitamin D GO:0051384 response to glucocorticoid stimulus GO:0032583 regulation of gene-specific transcription GO:0000187 activation of MAPK activity GO:0004716 receptor signaling protein tyrosine kinase activity GO:0032147 activation of protein kinase activity GO:0001934 positive regulation of protein amino acid phosphorylation GO:0045725 positive regulation of glycogen biosynthetic process |
| InterPro families | IPR000719 Protein kinase, catalytic domain IPR001245 Serine-threonine/tyrosine-protein kinase IPR001828 Extracellular ligand-binding receptor IPR011009 Protein kinase-like domain IPR017441 Protein kinase, ATP binding site IPR008266 Tyrosine-protein kinase, active site IPR002290 Serine/threonine-protein kinase domain IPR020635 Tyrosine-protein kinase, catalytic domain |
| Orthology group | MCL39774 |
Nucleotide sequence:
ATGTGCTCGCTGGTTTTATTTTTGTTGGTGCTGGTCTTGTCCTGGGACCGCTGTTATCAA
AGTCCGTGTTCGCTACTTCTACATCGACTTCGTGAGCGACCCACAGAGGAGCTGGCAGTT
CTGGTGAATGGACATCTTGTTGAGGTTGTTGTGTGGGGTGGCGGCGGGGCTCCGAGGGCG
GCGGCCGCTCTGCTGTTGGTGGCTCTTCGAGTCCGAGGATATCGGTCGCATCTACATGAA
GCAGCCCCCGATGTCTGTGGCCTCCTCGACATCTCGGACCTAAAAGAAGCTGCCGTCGTC
GCTCCAGCAGCGACGGTGCCGAGTGAGGACTGCAGACGTGCTGGCCTCGAGTTACTGACG
AACTTTTTGCAGCCTGCAGCGGTGTCTTATACTTTACATCTTTGGGCTCATGTGCCGTCG
GATCGATGTCGGTCACAAGCTGGACAATGGAGTTTCTATAAATATTATAAAGACATTGAT
GAGTGTGGATTTCTAAAAGCAAAGTTTTTTAACGATATTACTTATGGGTCATGTAGTAAT
TGTTTTGCGGTATTGACTCGAAATGAGAGCTTGGTCGACAATCAAATAGCAATGGAACTA
CAAACCCGAATCGACGCTGCGGAGCTGTTGTTACAGGTCGTGTCTTTTAAAAGTGACTTC
ATTATGCGCAAAACTATTTCTGAATTACGAAGACTCCAAAAACCATTTCTATTTGTTGAT
GAAGATTTGTGGTCTGATACTTTTGAAATGGTTTACGTTCAGCCTCCGCCGTGCGTCAGA
CATGTAAAAAATTGCATTCCCTTCATTAAAACTATCGGTAATCTTCGACTTGGTAATGGA
TGGTTCATGTATCAATTTGCACCCCCAATACTAGAATTAGTCAATGCACTTTCGCCAAAA
TCTAGCCAATTAAGAGAAATATTAAACATAGAGAGTGCACAGAATGAAAGCCACATCGAA
AACGCCGCTTGCTCGTGGGCCCTGCAGCACGTTGAAGAATTTAAGACTCTTATATTACAC
GACAAGCTCGAACAGAAAAAAGTTTTCGCTATCAAAATAATCCTGTGCAATCATGACCCT
TTAAACAAATATTTTGAAACTATAAGCGATTTAATTAATAGAGGTGAGTTTCAAAATAAT
ATTACACATATTGATTATAATATTTATAAGAACACAATAAATTGTTTCGACGAAGAACAT
TTTAGGCAAGTAATAACAAAAAACGCTCAAAAGAAAAATGTGGCTGGGGTCATAGCTTGG
AGTTGGTATAAGGGGACCACAGGTGCAGCGAAGGTAGCAGAACAAAGTCAACTTCCACTA
CTTCTGGCAGGAGCCGTAGCCGACGAGATACCACTCGGGTCAGCTGTTCGAGCAGCCTCA
GGGCGTCTCTCTGATTTAACAAGAGCTTTCCATTACATTTTGGAGAATTGTGGGTGGTCA
CGGATTGCCCTTTTATCAGATGATTCAGTTTATTCAAGAAGTTTCACAGAAGCAATGATC
AAGCAAAAGAATCTTCTGTATCGTGAAGTTATAGTAGACTTCAAAAATATTTATATAAAC
TTAGATGAATTAAAAAAAGCTGACGCACGTATATTTTTATTAAATGTAAATTGGAGCCTC
TCAAAAGACATTTTAAACGCTGCTCTAAAAAGAGGGATGACTCCTAACAATGGCTTCTCA
TGGATAGCTCGGGAATGGCTGCCAATACAGAACAATAACACAGACTGGGCTGACATGTAT
CACTTCACTGTGAGCCTGGGTTGGCGAGGAGAACAACTTGAAGGGGGATCGAAACATTTG
CAACAAAAGATTCGAAATCGGTTACATGTTAAAGAAAGTCTTGAAGAGTTTCCAGGCATC
AATTATTTATCAATGTTTGCAGATGCGCTGCTTCAATTGGGATATAGTTTTGCTCGATTT
TACCAAAACTACCCTTCTTACAGATACAATTTGCGTGGTTACGGAACTGCCTTAAAACTA
TCAGAAGTTTTTGAAAATATGACTATTAATGGAATAGCACAAAATTTAAGCAACAGAAAC
TCTAGCATCGAACACCCGCTTGTTTTTATTAATAAATGGTGGGGAGTGAGAACAAAGTCC
ATAGGTATATTGCAAATTACTGACAACTACATCATGGCTCTTAAACCAACAGCATCAAAT
TTCAAGGACTTAATAAATAGGCAAAAGTTACGGGATAGACCTATCTGCTGGACCATTAGC
ACAGGCGATCCTTTCACACCTCGCTGTCAGGACGTAACCATAATTATTGTGACAGTATTC
CTGCTTATTTCGGGAACAGCCCTTTACATTGCTCGACGAGCTCGATTGAAACGATTATTA
AAACGAGAATTAAATATACTAGCGAAACTGCTGGAGAATCGTAAACGTGCAGTCTCGTCA
CTGGATACGTATTTGGTTGATCGTAATGCCATAAAACTTTTACATGAAATAGGCTCTGGT
ACATTTGGGAGGGTCCATTTTGCCGAACTTCATCGATCAGGTCGCAGTACGGTGATCGTA
GCGGCCAAACAACCCCGACAAACCATTGGACCGACTGAAGAATGTGAATTTCTCCACGAA
GCGTACATCTTGGCGCCCTTGTGTCATGATAATATAATACGACTTGTTGGAATATGTATA
ATGAATGGACCTCCTATGGTTTTAATGGAACACGCCTATTATCTTGATTTGAAGCGTTAT
TTGACGGAGCGACGACATTTAGTGAGTAACCGGTTTAATGACAACACTTCCGATGCTTTG
GATGAGGTTTCGGATGAATCACTTACTAGACTAGCCCGAGAAGCGGCAGGAGCCCTGGCG
TATTTATCAACAAGAAGACTAGTGCATCGAGACGTGAGAGCTGCGAATTGTCTTATTGAT
AAGAAAAGATCCCTCAAACTTGGAGACTTCGGTATGGCACGCGAGCTGGACGACAAAGTT
CCAGTGTACGCTTCGATACGCCGTGCCTTGTTCCCTGTGTTGTGGATGGCACCCGAAAGT
TTAAAATCCGGAGTATTTTCTTTTGCAACAGATGTTTGGGCTCTCGGAATACTTATACTA
GAAGTTGTAACACTCGGTGCACGTCCTTACGGTGATTGGCAACTATCTCGTGTATTAAAC
TATGTGGTGGCCGGTGGAATTCCTCCACTTCCTCCGGATGTGTCAAAACATACGAGCAGT
TTGTTACACTCCTGTTGGGAACGTCGAGCAGAAAGCAGGCCAAATGCATCATGGGTGCAT
AACCATTTAACTCAGTATCCTCGATTGCTCTCTCCTGCTTTATTGAAACCGTATCCACCC
GATCCTCTTATCGCTTATATGGAATAA
Protein sequence:
MCSLVLFLLVLVLSWDRCYQSPCSLLLHRLRERPTEELAVLVNGHLVEVVVWGGGGAPRA
AAALLLVALRVRGYRSHLHEAAPDVCGLLDISDLKEAAVVAPAATVPSEDCRRAGLELLT
NFLQPAAVSYTLHLWAHVPSDRCRSQAGQWSFYKYYKDIDECGFLKAKFFNDITYGSCSN
CFAVLTRNESLVDNQIAMELQTRIDAAELLLQVVSFKSDFIMRKTISELRRLQKPFLFVD
EDLWSDTFEMVYVQPPPCVRHVKNCIPFIKTIGNLRLGNGWFMYQFAPPILELVNALSPK
SSQLREILNIESAQNESHIENAACSWALQHVEEFKTLILHDKLEQKKVFAIKIILCNHDP
LNKYFETISDLINRGEFQNNITHIDYNIYKNTINCFDEEHFRQVITKNAQKKNVAGVIAW
SWYKGTTGAAKVAEQSQLPLLLAGAVADEIPLGSAVRAASGRLSDLTRAFHYILENCGWS
RIALLSDDSVYSRSFTEAMIKQKNLLYREVIVDFKNIYINLDELKKADARIFLLNVNWSL
SKDILNAALKRGMTPNNGFSWIAREWLPIQNNNTDWADMYHFTVSLGWRGEQLEGGSKHL
QQKIRNRLHVKESLEEFPGINYLSMFADALLQLGYSFARFYQNYPSYRYNLRGYGTALKL
SEVFENMTINGIAQNLSNRNSSIEHPLVFINKWWGVRTKSIGILQITDNYIMALKPTASN
FKDLINRQKLRDRPICWTISTGDPFTPRCQDVTIIIVTVFLLISGTALYIARRARLKRLL
KRELNILAKLLENRKRAVSSLDTYLVDRNAIKLLHEIGSGTFGRVHFAELHRSGRSTVIV
AAKQPRQTIGPTEECEFLHEAYILAPLCHDNIIRLVGICIMNGPPMVLMEHAYYLDLKRY
LTERRHLVSNRFNDNTSDALDEVSDESLTRLAREAAGALAYLSTRRLVHRDVRAANCLID
KKRSLKLGDFGMARELDDKVPVYASIRRALFPVLWMAPESLKSGVFSFATDVWALGILIL
EVVTLGARPYGDWQLSRVLNYVVAGGIPPLPPDVSKHTSSLLHSCWERRAESRPNASWVH
NHLTQYPRLLSPALLKPYPPDPLIAYME