| New model in OGS2.0 | DPOGS213891 |
|---|---|
| Genomic Position | scaffold5651:- 8440-10941 |
| See gene structure | |
| CDS Length | 2502 |
| Paired RNAseq reads | 3544 |
| Single RNAseq reads | 7816 |
| Migratory profiles | Query via corresponding ESTs |
| Best Bmobyx hit | BGIBMGA003229 (7e-152) |
| Best Drosophila hit | HMG coenzyme A reductase, isoform C (0.0) |
| Best Human hit | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform 1 (6e-155) |
| Best NR hit (blastp) | RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase (0.0) |
| Best NR hit (blastx) | RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase; Short=HMG-CoA reductase (0.0) |
| GeneOntology terms | GO:0008354 germ cell migration GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity GO:0035232 germ cell attraction GO:0008406 gonad development GO:0005789 endoplasmic reticulum membrane GO:0008299 isoprenoid biosynthetic process GO:0005622 intracellular GO:0007280 pole cell migration GO:0015936 coenzyme A metabolic process GO:0016021 integral to membrane GO:0055114 oxidation reduction GO:0050661 NADP or NADPH binding GO:0035050 embryonic heart tube development |
| InterPro families | IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding IPR000731 Sterol-sensing domain IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site IPR004816 Hydroxymethylglutaryl-CoA reductase, metazoan IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/arcaheal type |
| Orthology group | MCL12308 |
Nucleotide sequence:
ATGAAGGTCTGGGGAGCGCACGGGGAGTTCTGTGCGAAACATCAATGGGAGGTCATAGTG
GCGACCCTCGCCCTCCTCGCCTGTGCTGCGAGTGTCGAGAGACACGGCACAGGCGTCAGA
TCTGAACACTGTGCGGGCTGGGCTAGAGCGTGTCCAGGGTTAGAGGCGGAGTATCAAGCG
GCCGACGCTGTTATCATGACCTTCGTCCGCTGCGCCGCCTTGCTCTACGCCTATTACCAA
GTGTCGAATCTTCAGAAAATTGCTTCGAAATATCTTCTAATAATTGCTGGCGTGTTCTCA
ACATTCGCCAGTTTCATATTCACGTCGGCATTGGCTAGTTTGTTTTGGAGCGAGCTGGCG
AGTATTAAGGATGCGCCGTTTCTGTTCCTATTGGTTGCTGATGTGGCTAGAGGGGCCAGG
ATGGCTAAGGCTGGATGGAGCGCAGGAGAGGATCAGGGGAAGAGGGTCGGCAAAGCGCTT
TCATTGCTGGGACCGACGGCGACTTTAGACACACTTCTAGCAGTTCTTCTAGTCGGTGTC
GGTGGACTATCTGGTGTTCCAAGATTGGAGCACATGTGCACGTTCGCTTGTCTGGCTCTG
TTAGTCGACTACTCCGTGTTCGTTACTTTCTACCCGGCCTGCTTATCGCTCGTGTCAGAT
TTCGCATCCGGCAGGAAAGAAATGAGACCGGATAGTCCGTTTGCTGAAAGTGATCTGAAA
CCTAACCCGGTGGTGCAGAGGGTCAAGATGATCATGGCTGCTGGTTTGTTGTGTGTACAT
CTGACAAGCAGGTTGCCGTGGGCGAAGGAGAACGGGATGATAGAAGGTTCCTTATCAAAA
GATTTCAAGTCGACATCCGATGAGAATGTTTTATTCAATTCGTACGTCAAATGGTTCTCA
GTGAGCGCCGATTATATCGTCATCGCCACGTTGTTGTGCGCTCTCATTATAAAATTCATC
TTCTTCGAGGAGCAAAGGAACTGGGTCATCGATATGAATGATCTAACGGTGAAGGAAGTC
ACTAATAAATATGACAAGCCTAAATTCATTGTTGGCGAGGAATTTAAAGCGGAGATATGT
ACTCAAACCGATGACCTGTTGAATTGGGAGGAGACCGAATGGCCAGTGCTCTCCCCGAGC
TCATCAGCCGCTAAACTTAACGCGAAAAAACGCCCAATGGCCGAATGTTTGGAAATATAC
CGTTCAGAGGGTGTCTGTACATCGCTTAGTGACGATGAAGTCGTAATGCTTGTGGAACAA
TCGCATATACCGTTGCATAGATTAGAGAATGTTCTCAACGATCCATTGCGCGGTGTCAGG
CTACGCAGGAGAGTCATATCGGCGAGATTCGAAACGGAATCTGCCGTGAAGAAGCTGCCT
TATCTCAACTACGACTATAGCAAAGTACTAAATGCGTGTTGCGAAAACGTGATTGGATAT
GTTGGTATTCCAGTAGGTTATGCTGGTCCCTTGGTCGTCGATGGTAAAGCTTATATGATC
CCCATGGCGACCACTGAAGGGGCTTTGGTAGCATCCACGAATAGAGGCGCTAAGGCAATT
GGAACCAGAGGAGTTACCAGTGTGGTTGAAGATGTGGGCATGACAAGAGCTCCAGCGGTG
AAGTTACCTAATGTAGTGCGAGCTCACGAGTGCCGTCAGTGGCTCGACAATAAAGATAAT
TACGCTATTATCAAAACGGCTTTCGATTCAACATCTAGATTCGCGCGACTCCAGGAAGTG
CACGTTGGCGTCGACGGCGCCATTTTATATTTGCGATTTAGAGCCACCACTGGCGACGCC
ATGGGAATGAACATGGTGTCTAAGGGTGCCGAAAACGCTCTCAAGCTACTCAAGAATTAC
TTCCCGGACATGGAAGTTATAAGTTTATCTGGCAATTACTGTTCTGATAAAAAAGCGGCT
TCAATCAACTGGGTCAAAGGTAGAGGCAAACGTGTAATATGCGAGACGACAATATCGGCT
ACAAATTTGAAGAATATTTTCAAAACTGACGCCAAAACTATGACAAGGTGCAACAAAATA
AAGAATTTGTCCGGATCGGCGTTGGCTGGTTCGATAGGAGGCAACAACGCTCACGCTGCT
AACATGGTCACCGCTATCTTCATAGCTACCGGCCAAGATCCAGCTCAGAATGTGACGAGC
AGCAACTGCTCCACCAGCATGGAGGTTTGTGGGGAGAACAACGAGGATCTGTATGTGACA
TGCACCATGCCTTCGTTGGAAGTAGGAACTGTTGGCGGCGGCACGGTTCTGACTGGTCAG
GGTGCCTGCCTCGAGATCCTCGGCGTCAAAGGAGCGGCGGAACGACCGGCTGAGAACTCA
GCCAGACTGGCTTCCCTAATATGCGCCACCGTCCTGGCCGGCGAGCTCAGCCTTATGGCC
GCTTTAGTCAACTCGGACTTAGTGAAATCTCACATGCGGCACAACAGATCCACTATCAAC
GTACAGAACGCGTCCAACGAACTGAAAGTACCCACATTATAA
Protein sequence:
MKVWGAHGEFCAKHQWEVIVATLALLACAASVERHGTGVRSEHCAGWARACPGLEAEYQA
ADAVIMTFVRCAALLYAYYQVSNLQKIASKYLLIIAGVFSTFASFIFTSALASLFWSELA
SIKDAPFLFLLVADVARGARMAKAGWSAGEDQGKRVGKALSLLGPTATLDTLLAVLLVGV
GGLSGVPRLEHMCTFACLALLVDYSVFVTFYPACLSLVSDFASGRKEMRPDSPFAESDLK
PNPVVQRVKMIMAAGLLCVHLTSRLPWAKENGMIEGSLSKDFKSTSDENVLFNSYVKWFS
VSADYIVIATLLCALIIKFIFFEEQRNWVIDMNDLTVKEVTNKYDKPKFIVGEEFKAEIC
TQTDDLLNWEETEWPVLSPSSSAAKLNAKKRPMAECLEIYRSEGVCTSLSDDEVVMLVEQ
SHIPLHRLENVLNDPLRGVRLRRRVISARFETESAVKKLPYLNYDYSKVLNACCENVIGY
VGIPVGYAGPLVVDGKAYMIPMATTEGALVASTNRGAKAIGTRGVTSVVEDVGMTRAPAV
KLPNVVRAHECRQWLDNKDNYAIIKTAFDSTSRFARLQEVHVGVDGAILYLRFRATTGDA
MGMNMVSKGAENALKLLKNYFPDMEVISLSGNYCSDKKAASINWVKGRGKRVICETTISA
TNLKNIFKTDAKTMTRCNKIKNLSGSALAGSIGGNNAHAANMVTAIFIATGQDPAQNVTS
SNCSTSMEVCGENNEDLYVTCTMPSLEVGTVGGGTVLTGQGACLEILGVKGAAERPAENS
ARLASLICATVLAGELSLMAALVNSDLVKSHMRHNRSTINVQNASNELKVPTL