Monarch geneset OGS2.0

DPOGS202280
TranscriptDPOGS202280-TA3537 bp
ProteinDPOGS202280-PA1178 aa
Genomic positionDPSCF300032 - 288065-291601
RNAseq coverage277x (Rank: top 39%)
Annotation
HeliconiusHMEL0047250.093.04% 
BombyxBGIBMGA004936-TA0.091.73% 
DrosophilaGef26-PA0.057.80% 
EBI UniRef50UniRef50_E2B4N90.071.28%Rap guanine nucleotide exchange factor 2 n=1 Tax=Harpegnathos saltator RepID=E2B4N9_HARSA
NCBI RefSeqXP_392340.30.070.69%PREDICTED: similar to Gef26 CG9491-PA [Apis mellifera]
NCBI nr blastpgi|3407133620.068.23%PREDICTED: rap guanine nucleotide exchange factor 6-like isoform 1 [Bombus terrestris]
NCBI nr blastxgi|3407133620.068.61%PREDICTED: rap guanine nucleotide exchange factor 6-like isoform 1 [Bombus terrestris]
Group
Gene OntologyGO:00072643.1e-61small GTPase mediated signal transduction
GO:00056223.1e-61intracellular
GO:00050853.1e-61guanyl-nucleotide exchange factor activity
GO:00510563.3e-24regulation of small GTPase mediated signal transduction
GO:00071656.9e-20signal transduction
GO:00055154.3e-18protein binding
KEGG pathwayame:4088100.0 
 K08018 (RAPGEF2, PDZGEF1)maps-> MAPK signaling pathway
InterPro domain[47-1043] IPR0089370Ras guanine nucleotide exchange factor
[209-1007] IPR0235782.1e-106Ras guanine nucleotide exchange factor, domain
[693-935] IPR0018953.2e-71Guanine-nucleotide dissociation stimulator CDC25
[244-356] IPR0006513.3e-24Ras-like guanine nucleotide exchange factor, N-terminal
[81-219] IPR0147106e-21RmlC-like jelly roll fold
[586-672] IPR0001596.9e-20Ras-association
[339-467] IPR0014784.3e-18PDZ/DHR/GLGF
[93-216] IPR0184902.4e-12Cyclic nucleotide-binding-like
Orthology groupMCL10981 Multiple-copy universal gene
Genotypes for resequenced monarchs and outgroup Danaus species

Nucleotide sequence:

>DPOGS202280-TA
ATGTTGAGAGGTGGGCGTGGTGGCCGTCACAGTCCGGAGCTGTATCCTCACACACTCAAGTGTTCAAACGCCAGTGACACAAGTTCTGCATACAGTGGCAGCGACACAATGACTTCAGTACACAGCTCTTTGGATATGGATATGGAGGTAGATCTGTCTGGCCTCCTCGAGTCTATAGTGGATTCTGAGGAGGAAGAAGATTTAGAGGAGAGTATGGACAGTTTGACTGTCCGTGATGCTGTAAGAGAATGCCTTGAGAAAGATCCAAGTGAAAGAACAGATGAGGATATAGAAATTCTTCTAGAATTTACTCAACACTTAAAAGCTTTTACTAACATGACTCTGACAGTAAGGAGGGCTCTGTGTGCTGTTATGGTTTTTGCTGTTGTTGAAAAAGCTGAAACAGTTGTTATGAATGATGGTGAGGAACATGACTCATGGTCTGTTCTTATCAATGGGCAAGTTGGTATTGAGCATCAAAATGGAGACATTGAGTACCTGAATGTAGGTGATAGTTTTGGTATGGCGGAAGCTACTTTGGAGAAACTATATCACCGAGGGATTATGACTACTAGATGTGATGATTGCCAATTTGTTTGTGTTACTCAAACAGATTATTACCGCATTTTACATCAAGGTGAAGAGAACATCAAAAGGCATGAAAATGAAAATGGTGTAATAGTTCTTGTAACTGAATATAGAGGGGCAGCAGGGGATTCTGGTCATCAACAAGGTCATGTAGTAATAAGAGGGACACCGGAACATTTGATGCTTCAACTTATTGAAGACAACTCACGTGATTCCACATATGTTGAAGATTTCTTATTAACTCACAGAACTTTTATAGAGAGCCCACTGGTTGTGGCAAAACAGTTGCTTGCCTGGTTTTCGGAACCATCAGTTCGTGATAAAGTCACAAGAGTTGTACTTCTTTGGGTGAATAATCATTTCACTGACTTTGAAACGGACCCCAACATGATGGAGTTCCTGGAGAACTTTGAAATGGCTTTAGAACAAGAAAAAATGGAATCACAGTTAAGATTGTTAAACATTGCCTGTTCTGCGAAAGCAAGGACCAGGAGTGTAACTTTGTCTCGACCAACAAGAGATGAGCCATTATATTTTTCTATATTGGGAGGATATGAAAGGGGATATGGAATCTTTGTCTTGAAAGTTGAAAAACATTCGAAAGCTGAAGATGTAGGTTTGAAACGTGGAGATCAGATATTGGAAGTGAATTGTCAATCATTTCAACATGTAAGTCACGCAAAAGCCATGGAAATAATTACGGGTTCCACACATTTGAGCATTACAGTTAAAAGTAATCTATTAGCATTTAAGCAGATGATGTTAATGCCAGAAAACTCTCCGAGACAAAGAGGGGGCGCAAATATGGTTCGCTGGCAAACGGACCCCAGAGCTAGATTGTCAACAGCAGAACTCCTGAGTGATGACCCCATCACATTGACACCAATGTTCCAATCTCCAACCAAAAAACCGCAACAAATGAATATCAAAAAGGAGCCCCAAAAAGGTTTTATGACATTGGGTCCTAAAAGGAGATTGCAAAAAGCTTTGATGAAAATGAACATACTTCCTAAAAATACTATCAATGATGGCATTCATAATGATGATAGTGTTCTCTCACATTCTGAGTCATTGCACAAACCTAATTCCAGTACATCATTCTACAACTCACACAGCAACCCAGATCTCATATCAATATGTTACGATGAATATCAATCATCAGACTATCCTGAACATGTACTAAAAGTCTATAGAGCCGATCAAACATGCAAATACTTGTTAGTACACAAAGAGACAACTGCTAGAGAAGTTGTCATGCTTACTCTACAAGAGTTTGGTATAACCGATCCTAGTTCAAATTTTTCCTTATGTGAAGTGTCTGTAGCACAAGGAGGCATAATAAAACAACACCGCCTACCAGATCAGTTGCAAAATCTCGCTGAGCGTATTGGACTGAGTTCAAGGTACTATTTGAAGACAAATGGCGTAAGTGAAACATTAGTGCCAGACGAAATGGCACCAGAGCTTCTAAGGGAAAGTGTTGTACATTTCTTACAACTTAATGCTGTTGAAGTCGCTGTGCAATTAACCTTACAGGATTTCTGTATATTCCGACAGATTGAAAGCACCGAATATGTTGACGATTTGTTTGATTTAAAAAGTAGGTATGGAACACCCATGTTATCCCAGTTTGCTGGTTTGGTTAACAAAGAAATGTTCTGGGTCGTGACCGAGGTCGTCAATGAACAAAATATTGTGAGAAGATCCAAAATCATAAAACAGTTCATAAAAGTAGCTCGTCATTGCAAAGAGTGTAAGAATTTCAATTCTATGTTCGCTATCATTTCTGGCTTAGGACATGGGGCCGTATCTAGATTAAGAATGACTTGGGAAAAATTACCCACGAAATATAACAAGCTGTTCTCTGATCTTCAAATGCTGATGGATCCTTCCAGAAATATGTCCAAATATCGTCAGTTAGTAACAATAGAGCAAGGAAGATCGCCAGTGATACCATTCTATCCAGTTGTTAGAAAAGATTTAACATTCATTCATCTCGGTAATGATACGAAAGTGGAAGGGATGGTTAATTTTGAAAAGTTGCGCATGATTGCTAAGGAGGTACGAACTCTGACCAATATGTGCAGTTCGCCATATGATCTCCTCACACTGTTAGAACTAGGGAAACAGCCACCGTCTAATGCTATGGTTGCCTTGAATCAACTTACAACAGGAGTCCAACAAGGACAGGTGACAGTTAAAAGAAGGAAGAAATCTTCCAACGTTCCTAATCCGAAAAAGATGTTTGAAGAAGCACAGATGGTCCGGAGAGTTAAAGCATATCTAAATAGAATGCATGTAGAAACAGATGAAGAACGTCTTCATGCATTGTCTCTAGAATGCGAAGGTTCCGGACCTGCTCCAACTATGCCGCGACGACGGCATCCTTCGCCTTCCCTTTCCACGACCAGTAGCGCTTCGTCAGCAAGCGAGAGTAAGAAGAGTTTCGCCGGAAATAAGTTTGGAGCAGCTTCCCCGCAGGCTGTACGAAAGCTACTGGCTTTATCTGAGCCTGCTAAGACCAGACCTCATCAACCCAGGCCCGCTCCTCCGGGCCCGTCGCCTTGCTCGCAACGTCGGGACGGTCATCCTGGGTCCGGGATATGTTGTTCCCGTGCAGCGCACGAGAGATCGCATTCGGATACGCCGACGCCATTGCCCGTGGACTTATCGGCGGAGAGTAGCAGTGTGACGTCATTAGTAAACTTGCCATTAAGGAAGACCGGGTCAGCTACATCTAGCGACAGTGGCCACGGTTCATGTACGACGGCAAACTGCGTTCGACCGCTTCCACCCATACCCAGGATGCCGTACACCCTCGCCGCACAGGTCGCCCGTCTGGAACGACTCAGCCGTGCGCACTCGCACGAGGGTGTCACCCGCTCGTACGATTACTATCACGATGCTCCAGACGACGAGGATGACGACCAGCAGGTGTCCGCTGTTTAA

Protein sequence:

>DPOGS202280-PA
MLRGGRGGRHSPELYPHTLKCSNASDTSSAYSGSDTMTSVHSSLDMDMEVDLSGLLESIVDSEEEEDLEESMDSLTVRDAVRECLEKDPSERTDEDIEILLEFTQHLKAFTNMTLTVRRALCAVMVFAVVEKAETVVMNDGEEHDSWSVLINGQVGIEHQNGDIEYLNVGDSFGMAEATLEKLYHRGIMTTRCDDCQFVCVTQTDYYRILHQGEENIKRHENENGVIVLVTEYRGAAGDSGHQQGHVVIRGTPEHLMLQLIEDNSRDSTYVEDFLLTHRTFIESPLVVAKQLLAWFSEPSVRDKVTRVVLLWVNNHFTDFETDPNMMEFLENFEMALEQEKMESQLRLLNIACSAKARTRSVTLSRPTRDEPLYFSILGGYERGYGIFVLKVEKHSKAEDVGLKRGDQILEVNCQSFQHVSHAKAMEIITGSTHLSITVKSNLLAFKQMMLMPENSPRQRGGANMVRWQTDPRARLSTAELLSDDPITLTPMFQSPTKKPQQMNIKKEPQKGFMTLGPKRRLQKALMKMNILPKNTINDGIHNDDSVLSHSESLHKPNSSTSFYNSHSNPDLISICYDEYQSSDYPEHVLKVYRADQTCKYLLVHKETTAREVVMLTLQEFGITDPSSNFSLCEVSVAQGGIIKQHRLPDQLQNLAERIGLSSRYYLKTNGVSETLVPDEMAPELLRESVVHFLQLNAVEVAVQLTLQDFCIFRQIESTEYVDDLFDLKSRYGTPMLSQFAGLVNKEMFWVVTEVVNEQNIVRRSKIIKQFIKVARHCKECKNFNSMFAIISGLGHGAVSRLRMTWEKLPTKYNKLFSDLQMLMDPSRNMSKYRQLVTIEQGRSPVIPFYPVVRKDLTFIHLGNDTKVEGMVNFEKLRMIAKEVRTLTNMCSSPYDLLTLLELGKQPPSNAMVALNQLTTGVQQGQVTVKRRKKSSNVPNPKKMFEEAQMVRRVKAYLNRMHVETDEERLHALSLECEGSGPAPTMPRRRHPSPSLSTTSSASSASESKKSFAGNKFGAASPQAVRKLLALSEPAKTRPHQPRPAPPGPSPCSQRRDGHPGSGICCSRAAHERSHSDTPTPLPVDLSAESSSVTSLVNLPLRKTGSATSSDSGHGSCTTANCVRPLPPIPRMPYTLAAQVARLERLSRAHSHEGVTRSYDYYHDAPDDEDDDQQVSAV-