Monarch geneset OGS2.0

DPOGS203565
TranscriptDPOGS203565-TA1512 bp
ProteinDPOGS203565-PA503 aa
Genomic positionDPSCF300055 + 625809-629161
RNAseq coverage2233x (Rank: top 5%)
Annotation
HeliconiusHMEL0028340.087.14% 
BombyxBGIBMGA008304-TA0.078.93% 
DrosophilaAkt1-PC0.066.06% 
EBI UniRef50UniRef50_Q8INB90.066.06%RAC serine/threonine-protein kinase n=24 Tax=Bilateria RepID=AKT1_DROME
NCBI RefSeqXP_968049.20.069.82%PREDICTED: similar to rac serine/threonine kinase [Tribolium castaneum]
NCBI nr blastpgi|3437966230.087.28%serine/threonine protein kinase Akt [Helicoverpa armigera]
NCBI nr blastxgi|3437966230.087.45%serine/threonine protein kinase Akt [Helicoverpa armigera]
Group
Gene OntologyGO:00055241.7e-103ATP binding
GO:00046741.7e-103protein serine/threonine kinase activity
GO:00064681.7e-103protein phosphorylation
GO:00167726.2e-94transferase activity, transferring phosphorus-containing groups
GO:00046726.2e-72protein kinase activity
GO:00055156e-22protein binding
GO:00047131.8e-11protein tyrosine kinase activity
KEGG pathwaytca:6564230.0 
 K04456 (AKT)maps-> Prostate cancer
    Fc epsilon RI signaling pathway
    Toll-like receptor signaling pathway
    MAPK signaling pathway
    Fc gamma R-mediated phagocytosis
    Glioma
    B cell receptor signaling pathway
    Melanoma
    Pathways in cancer
    Chemokine signaling pathway
    Adipocytokine signaling pathway
    Endometrial cancer
    Chagas disease
    Insulin signaling pathway
    Neurotrophin signaling pathway
    T cell receptor signaling pathway
    Focal adhesion
    ErbB signaling pathway
    Colorectal cancer
    mTOR signaling pathway
    Tight junction
    Progesterone-mediated oocyte maturation
    Apoptosis
    Renal cell carcinoma
    Small cell lung cancer
    Pancreatic cancer
    Acute myeloid leukemia
    Non-small cell lung cancer
    Jak-STAT signaling pathway
    Chronic myeloid leukemia
    VEGF signaling pathway
InterPro domain[158-415] IPR0022901.7e-103Serine/threonine-protein kinase domain
[153-499] IPR0110096.2e-94Protein kinase-like domain
[158-415] IPR0174426.2e-72Serine/threonine-protein kinase-like domain
[7-114] IPR0119936e-22Pleckstrin homology-type
[416-480] IPR0009611.1e-16AGC-kinase, C-terminal
[9-112] IPR0018493.6e-16Pleckstrin homology domain
[158-410] IPR0206351.8e-11Tyrosine-protein kinase, catalytic domain
[435-478] IPR0178922.6e-10Protein kinase, C-terminal
Orthology groupMCL11287 Multiple-copy universal gene
Genotypes for resequenced monarchs and outgroup Danaus species

Nucleotide sequence:

>DPOGS203565-TA
ATGGCGGAGGCGGCGCCCGGGAATATCGTGAAGGAGGGCTGGTTGCTGAAGCGCGGCGAGCACATCCGTAACTGGCGCGACCGCTACTTCATCCTGTTCGACAATGGCGACCTACTGGGATTCAAGGCGCAGCCCGAGCGCAACAACTACCGTGACACCCTCAACAAGTTTACAGTGCGCGATTGTCAGATCATGGCTGTAGACAAACCCCGGCCCTACGTGTTCACGATTCGTGGCCTACAGTGGACTACCGTCATAGAAAGAAACTTCGCCGTCGACAACGAGAAGGATCGCGAGGAGTGGGTGGCGGCTATCCGCTATGTATCGTCGACCCTGGCGGCGGGCTCGGCGGCCGGGGAGGGTGCGTCGGGGGCTCTCGGCGGTGTTCTCCCTCCGCACGACACCGACGACGATGACATCGCCAAGCTCGGCACCAGCTTCAGGGATCCGAGACGCATCACCTTGGAGAAGTTTGAGTTCGTGAAGGTCCTGGGGAAGGGGACCTTCGGGAAGGTGGTGCTCAGTAGAGAAAAGGGAACCGGCAAGCTTTACGCCATGAAGATACTGAAGAAACACATCATCATACAGAAGGACGAGGTCGCGCACACCATCACCGAGAACCACGTGCTCAAGAAGACCAAACATCCATTCCTTACGGCGCTGCGTTACTCGTTCCAAACGGCAGACCGCGTGTGTTTCGTGATGGAGTACGCCAACGGCGGGGAACTGTTCTTTCATCTTTCGCGAGTGAGATCCTTCAGCGAGGAGCGGACGCGCTTCTACGGCGCCGAGATCGTGGCGGCGCTGGGGTACCTGCATGCCGAGGGCATCATATACAGGGATCTTAAGCTTGAGAATCTTCTCCTGGACAAGGACGGCCACATCAAGATCGCCGACTTCGGACTGTGCAAGGTCGACATCACGTACGGCCGGACGACCAAGACGTTCTGCGGCACTCCGGAGTACCTCGCGCCCGAGGTGCTGGAGGACACGGATTACGGGCCGGCCGTGGACTGGTGGGGCACCGGCGTGGTGCTGTACGAGATGGTGTGCGGTCGCCTGCCCTTCTACAACAGGGACCACGAGGTGCTGTTCGAGCTCATCTTGCAGGAGGAGGTGCGCTTCCCCCGCGCGTTGTCGGCCGCCTGCCGCTCGCTGCTGGCCGGCCTGCTGTGCAAGGAGCCCGCCGGCCGCCTGGGCGCCGGCCCCGACGACGCCAAGGAGATCATGCAGCATCCCTTCTTCACGTCCGTCAACTGGAGCGACCTCGTCGCCAAGAAGATTCCGCCGCCCTTCAAGCCGCAGGTGGACTCGGACACCGACACGCGCTACTTCGACTCGGAGTTCACGGGCGAATCCGTGGAACTCACGCCGCCCGATAACGACTCCGGCCTCGCGCGCATCCAGGAGGAGCACTTCCCGCAGTTCTCGTACCAGGACATCTGCTCGTCGGCGCACTCGGCCCTGTCTCACCTGTCGCACCACTCCGCCGCGCCCGACCGCCGCCACTAG

Protein sequence:

>DPOGS203565-PA
MAEAAPGNIVKEGWLLKRGEHIRNWRDRYFILFDNGDLLGFKAQPERNNYRDTLNKFTVRDCQIMAVDKPRPYVFTIRGLQWTTVIERNFAVDNEKDREEWVAAIRYVSSTLAAGSAAGEGASGALGGVLPPHDTDDDDIAKLGTSFRDPRRITLEKFEFVKVLGKGTFGKVVLSREKGTGKLYAMKILKKHIIIQKDEVAHTITENHVLKKTKHPFLTALRYSFQTADRVCFVMEYANGGELFFHLSRVRSFSEERTRFYGAEIVAALGYLHAEGIIYRDLKLENLLLDKDGHIKIADFGLCKVDITYGRTTKTFCGTPEYLAPEVLEDTDYGPAVDWWGTGVVLYEMVCGRLPFYNRDHEVLFELILQEEVRFPRALSAACRSLLAGLLCKEPAGRLGAGPDDAKEIMQHPFFTSVNWSDLVAKKIPPPFKPQVDSDTDTRYFDSEFTGESVELTPPDNDSGLARIQEEHFPQFSYQDICSSAHSALSHLSHHSAAPDRRH-