| id | GO:0030433 Detailed information
|
|---|
| name | ER-associated protein catabolic process
|
|---|
| namespace | biological_process
|
|---|
| def | "The chemical reactions and pathways resulting in the breakdown of proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation. This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins." [GOC:mah, GOC:rb, PMID:14607247, PMID:19520858]
|
|---|
| comment | See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.
|
|---|
| synonym | "endoplasmic reticulum-associated protein catabolic process" EXACT []
|
|---|
| synonym | "endoplasmic reticulum-associated protein catabolism" EXACT []
|
|---|
| synonym | "ER-associated protein breakdown" EXACT []
|
|---|
| synonym | "ER-associated protein catabolism" EXACT []
|
|---|
| synonym | "ER-associated protein degradation" EXACT []
|
|---|
| synonym | "ERAD" EXACT []
|
|---|
| is_a | GO:0043161 ! proteasomal ubiquitin-dependent protein catabolic process
|
|---|