| id | GO:0004221 Detailed information
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| name | ubiquitin thiolesterase activity
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| namespace | molecular_function
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| alt_id | GO:0008577
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| def | "Catalysis of the reaction: ubiquitin C-terminal thiolester + H2O = ubiquitin + a thiol. Hydrolysis of esters, including those formed between thiols such as dithiothreitol or glutathione and the C-terminal glycine residue of the polypeptide ubiquitin, and AMP-ubiquitin." [EC:3.1.2.15]
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| comment | Note that this term is distinguished from 'ubiquitin-specific protease activity ; GO:0004843' in that it specifically refers to hydrolysis of thiolester bonds, but encompasses the removal of any substrate attached to ubiquitin via a thiolester bond.
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| subset | gosubset_prok
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| synonym | "ubiquitin C-terminal hydrolase activity" RELATED []
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| synonym | "ubiquitin carboxy-terminal esterase activity" EXACT [EC:3.1.2.15]
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| synonym | "ubiquitin carboxy-terminal hydrolase activity" RELATED [EC:3.1.2.15]
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| synonym | "ubiquitin thioesterase activity" EXACT [EC:3.1.2.15]
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| synonym | "ubiquitin-C-terminal-thioester hydrolase activity" EXACT [EC:3.1.2.15]
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| synonym | "ubiquitinyl hydrolase 1 activity" NARROW []
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| xref | EC:3.1.2.15
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| xref | MetaCyc:UBIQUITIN-THIOLESTERASE-RXN
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| is_a | GO:0016790 ! thiolester hydrolase activity
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