New model in OGS2.0 | DPOGS202058  |
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Genomic Position | scaffold356:- 113945-120716 |
See gene structure | |
CDS Length | 456 |
Paired RNAseq reads   | 12 |
Single RNAseq reads   | 264 |
Migratory profiles | Query via corresponding ESTs |
Best Bmobyx hit | BGIBMGA012534 (1e-43) |
Best Drosophila hit   | hedgehog, isoform B (1e-22) |
Best Human hit | sonic hedgehog protein preproprotein (3e-24) |
Best NR hit (blastp)   | hedgehog protein [Daphnia magna] (1e-27) |
Best NR hit (blastx)   | hedgehog [Tribolium castaneum] (3e-29) |
GeneOntology terms    | GO:0060425 lung morphogenesis GO:0060428 lung epithelium development GO:0010463 mesenchymal cell proliferation GO:0060174 limb bud formation GO:0010628 positive regulation of gene expression GO:0060173 limb development GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter GO:0048839 inner ear development GO:0060438 trachea development GO:0060021 palate development GO:0021521 ventral spinal cord interneuron specification GO:0014706 striated muscle tissue development GO:0014902 myotube differentiation GO:0014858 positive regulation of skeletal muscle cell proliferation GO:0060070 canonical Wnt receptor signaling pathway GO:0060442 branching involved in prostate gland morphogenesis GO:0048808 male genitalia morphogenesis GO:0060406 positive regulation of penile erection GO:0021938 smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation GO:0060020 Bergmann glial cell differentiation GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0002052 positive regulation of neuroblast proliferation GO:0021904 dorsal/ventral neural tube patterning GO:0021978 telencephalon regionalization GO:0014003 oligodendrocyte development GO:0070447 positive regulation of oligodendrocyte progenitor proliferation GO:0048864 stem cell development GO:0021940 positive regulation of granule cell precursor proliferation GO:0048856 anatomical structure development GO:0021513 spinal cord dorsal/ventral patterning GO:0002076 osteoblast development GO:0010468 regulation of gene expression GO:0048859 formation of anatomical boundary GO:0002053 positive regulation of mesenchymal cell proliferation GO:0060439 trachea morphogenesis GO:0060441 epithelial tube branching involved in lung morphogenesis GO:0060463 lung lobe morphogenesis GO:0060458 right lung development GO:0060484 lung-associated mesenchyme development GO:0060459 left lung development GO:0080125 multicellular structure septum development GO:0060916 mesenchymal cell proliferation involved in lung development GO:0060840 artery development GO:0060445 branching involved in salivary gland morphogenesis GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060516 primary prostatic bud elongation GO:0060684 epithelial-mesenchymal cell signaling GO:0060685 regulation of prostatic bud formation GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development GO:0090090 negative regulation of canonical Wnt receptor signaling pathway GO:0060513 prostatic bud formation GO:0090041 negative regulation of gene-specific transcription elongation from RNA polymerase II promoter GO:0060523 prostate epithelial cord elongation GO:0060662 salivary gland cavitation GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development GO:0071285 cellular response to lithium ion GO:0072199 regulation of mesenchymal cell proliferation involved in ureter development GO:0072193 ureter smooth muscle cell differentiation GO:0060783 mesenchymal smoothened signaling pathway involved in prostate gland development GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development GO:0060782 regulation of mesenchymal cell proliferation involved in prostate gland development GO:0060447 bud outgrowth involved in lung branching GO:0043587 tongue morphogenesis GO:0048709 oligodendrocyte differentiation GO:0048678 response to axon injury GO:0048714 positive regulation of oligodendrocyte differentiation GO:0043588 skin development GO:0048663 neuron fate commitment GO:0048754 branching morphogenesis of a tube GO:0048557 embryonic digestive tract morphogenesis GO:0048643 positive regulation of skeletal muscle tissue development GO:0048568 embryonic organ development GO:0048645 organ formation GO:0031069 hair follicle morphogenesis GO:0048706 embryonic skeletal system development GO:0048617 embryonic foregut morphogenesis GO:0048598 embryonic morphogenesis GO:0048646 anatomical structure formation involved in morphogenesis GO:0001948 glycoprotein binding GO:0048589 developmental growth GO:0001942 hair follicle development GO:0001944 vasculature development GO:0048546 digestive tract morphogenesis GO:0001947 heart looping GO:0016787 hydrolase activity GO:0016020 membrane GO:0005576 extracellular region GO:0008233 peptidase activity GO:0007154 cell communication GO:0005886 plasma membrane GO:0005515 protein binding GO:0016563 transcription activator activity GO:0005113 patched binding GO:0005783 endoplasmic reticulum GO:0005794 Golgi apparatus GO:0030133 transport vesicle GO:0005615 extracellular space GO:0005634 nucleus GO:0005624 membrane fraction GO:0005539 glycosaminoglycan binding GO:0042733 embryonic digit morphogenesis GO:0043193 positive regulation of gene-specific transcription GO:0030850 prostate gland development GO:0001841 neural tube formation GO:0030900 forebrain development GO:0030902 hindbrain development GO:0030901 midbrain development GO:0048468 cell development GO:0051146 striated muscle cell differentiation GO:0043237 laminin-1 binding GO:0031016 pancreas development GO:0043066 negative regulation of apoptosis GO:0051152 positive regulation of smooth muscle cell differentiation GO:0051151 negative regulation of smooth muscle cell differentiation GO:0051155 positive regulation of striated muscle cell differentiation GO:0035115 embryonic forelimb morphogenesis GO:0035116 embryonic hindlimb morphogenesis GO:0031012 extracellular matrix GO:0030878 thyroid gland development GO:0001822 kidney development GO:0048314 embryo sac morphogenesis GO:0043010 camera-type eye development GO:0042476 odontogenesis GO:0045471 response to ethanol GO:0045666 positive regulation of neuron differentiation GO:0046534 positive regulation of photoreceptor cell differentiation GO:0046639 negative regulation of alpha-beta T cell differentiation GO:0042475 odontogenesis of dentine-containing tooth GO:0009952 anterior/posterior pattern formation GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:0045449 regulation of transcription GO:0045445 myoblast differentiation GO:0042307 positive regulation of protein import into nucleus GO:0045165 cell fate commitment GO:0045597 positive regulation of cell differentiation GO:0045109 intermediate filament organization GO:0009790 embryo development GO:0001708 cell fate specification GO:0045596 negative regulation of cell differentiation GO:0009953 dorsal/ventral pattern formation GO:0009986 cell surface GO:0045121 membrane raft GO:0001755 neural crest cell migration GO:0007596 blood coagulation GO:0007275 multicellular organismal development GO:0042127 regulation of cell proliferation GO:0008284 positive regulation of cell proliferation GO:0007389 pattern specification process GO:0007267 cell-cell signaling GO:0007165 signal transduction GO:0007411 axon guidance GO:0001570 vasculogenesis GO:0030326 embryonic limb morphogenesis GO:0007224 smoothened signaling pathway GO:0030162 regulation of proteolysis GO:0001569 patterning of blood vessels GO:0007368 determination of left/right symmetry GO:0006915 apoptosis GO:0008283 cell proliferation GO:0008219 cell death GO:0007398 ectoderm development GO:0016539 intein-mediated protein splicing GO:0006508 proteolysis GO:0007228 positive regulation of hh target transcription factor activity GO:0001525 angiogenesis GO:0001656 metanephros development GO:0042130 negative regulation of T cell proliferation GO:0007502 digestive tract mesoderm development GO:0030178 negative regulation of Wnt receptor signaling pathway GO:0007442 hindgut morphogenesis GO:0007507 heart development GO:0042177 negative regulation of protein catabolic process GO:0030324 lung development GO:0006897 endocytosis GO:0030010 establishment of cell polarity GO:0030336 negative regulation of cell migration GO:0030323 respiratory tube development GO:0008209 androgen metabolic process GO:0030539 male genitalia development GO:0007417 central nervous system development GO:0007405 neuroblast proliferation GO:0001658 branching involved in ureteric bud morphogenesis GO:0030177 positive regulation of Wnt receptor signaling pathway |
InterPro families    | IPR009045 Hedgehog/DD-peptidase, zinc-binding motif IPR000320 Hedgehog, N-terminal signaling domain |
Orthology group | MCL19667 |
Nucleotide sequence:
ATGAGGCTAACGCTGGTGCTACTGTGGCTGGGCGCTGCGGCGGCCTGTGGCCCGGGCCGT
GGCTTCACCCGCCGCCACGGACCGCGCCGCATAACGCCCCTCGTCTTCAACCAGCACGAC
CCTAACATCAACGAGAACTCCAAGTCAGCCAGCGGACCCCCAGAGGGACGTATCACTAGA
AACGACGAGAAATTCAAAGACTTAGTGCCAAATTATAATCCGGATATAGACTTCAAGGAT
GAAGAGGGCACGGGTGCCGATCGGCTCATGACACAGTTTCAAAGCGACCGGCGATCGAGT
CCAGGCGCCGCGGGATGCCGGCGTGTCCCCGGGCCCCGTACCCCTTACCTTTATTTATAT
TTATTTACCTTCCCTTCATTCAACGAAGGGCCGCCCTTTCGGCCCTTTTTGTCGCCCCGA
TACAAATATTGTGAAAGAGGCCTGCGGTTGGAGTAA
Protein sequence:
MRLTLVLLWLGAAAACGPGRGFTRRHGPRRITPLVFNQHDPNINENSKSASGPPEGRITR
NDEKFKDLVPNYNPDIDFKDEEGTGADRLMTQFQSDRRSSPGAAGCRRVPGPRTPYLYLY
LFTFPSFNEGPPFRPFLSPRYKYCERGLRLE