id | GO:0005675   Detailed information |
---|---|
  name | holo TFIIH complex |
  namespace | cellular_component |
  def | "A complex that contains kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. In S. cerevisiae, it is composed of the 5-subunit core (Rad3p, Tfb1p, Tfb2p, Ssl1p and Tfb4p), Ssl2p, and TFIIK (Kin28p, Ccl1p, and Tfb3p). All of the subunits have equivalents in humans: the 5 subunit core is composed of ERCC2, p62, p55, p44, p34; the equivalent of the TFIIK subcomplex is composed of MO15, Mat1, and a cyclin; the human equivalent of Ssl2p is XPB." [GOC:krc, PMID:14500720, PMID:7813015] |
  is_a | GO:0005667 ! transcription factor complex |
  relationship | part_of GO:0016591 ! DNA-directed RNA polymerase II, holoenzyme |
  DPGLEAN03506
  DPGLEAN06048
  DPGLEAN08961
  DPGLEAN10133
  DPGLEAN10282
  DPGLEAN13348
  DPGLEAN14269
  DPGLEAN14392
  DPGLEAN16265
  DPGLEAN18066
  DPGLEAN19668
  DPGLEAN19783