id | GO:0005852   Detailed information |
---|---|
  name | eukaryotic translation initiation factor 3 complex |
  namespace | cellular_component |
  def | "A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs." [PMID:15904532] |
  synonym | "eIF-3" EXACT [] |
  synonym | "eIF3" EXACT [] |
  is_a | GO:0043234 ! protein complex |
  is_a | GO:0044444 ! cytoplasmic part |
  DPGLEAN00625
  DPGLEAN00664
  DPGLEAN01592
  DPGLEAN03764
  DPGLEAN03863
  DPGLEAN04272
  DPGLEAN04410
  DPGLEAN04503
  DPGLEAN08116
  DPGLEAN09663
  DPGLEAN09716
  DPGLEAN13779
  DPGLEAN15465
  DPGLEAN15623
  DPGLEAN19652
  DPGLEAN21190