id | GO:0006342   Detailed information |
---|---|
  name | chromatin silencing |
  namespace | biological_process |
  alt_id | GO:0016440 |
  def | "Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin." [GOC:mah, PMID:10219245] |
  comment | Note that this process is the opposite of chromatin-mediated maintenance of transcription. This regulation is exemplified by members of the Polycomb group, which maintain the inactive state of homeotic gene transcription. |
  synonym | "chromatin-mediated maintenance of transcriptional inactivation" EXACT [] |
  synonym | "chromatin-mediated silencing" EXACT [] |
  synonym | "heterochromatic silencing" RELATED [] |
  synonym | "TGS" EXACT [] |
  synonym | "transcriptional gene silencing" EXACT [] |
  is_a | GO:0016458 ! gene silencing |
  is_a | GO:0045814 ! negative regulation of gene expression, epigenetic |
  is_a | GO:0045892 ! negative regulation of transcription, DNA-dependent |
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