| id | GO:0006260 Detailed information
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| name | DNA replication
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| namespace | biological_process
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| alt_id | GO:0055133
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| def | "The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA." [GOC:mah]
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| comment | See also the biological process terms 'DNA-dependent DNA replication ; GO:0006261' and 'RNA-dependent DNA replication ; GO:0006278'.
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| subset | goslim_pir
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| subset | goslim_pombe
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| subset | gosubset_prok
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| xref | Reactome:1235837 "Recruitment of Rad17-RFC complex to DNA"
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| xref | Reactome:1235846 "Recruitment and activation of Chk1"
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| xref | Reactome:1235848 "Stalling of DNA replication fork and RPA binding"
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| xref | Reactome:1235850 "Binding of ATR-ATRIP to the RPA-ssDNA complex"
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| xref | Reactome:1235870 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:1235886 "Activation of claspin"
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| xref | Reactome:1235887 "Loading of claspin onto DNA during replication origin firing"
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| xref | Reactome:1252909 "Activation of ATR in response to replication stress"
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| xref | Reactome:1263117 "Recruitment of Rad17-RFC complex to DNA"
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| xref | Reactome:1263126 "Recruitment and activation of Chk1"
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| xref | Reactome:1263128 "Stalling of DNA replication fork and RPA binding"
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| xref | Reactome:1263130 "Binding of ATR-ATRIP to the RPA-ssDNA complex"
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| xref | Reactome:1263154 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:1263163 "Activation of claspin"
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| xref | Reactome:1263164 "Loading of claspin onto DNA during replication origin firing"
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| xref | Reactome:1279843 "Activation of ATR in response to replication stress"
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| xref | Reactome:1287756 "Recruitment and activation of Chk1"
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| xref | Reactome:1298862 "Activation of ATR in response to replication stress"
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| xref | Reactome:1309475 "Recruitment of Rad17-RFC complex to DNA"
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| xref | Reactome:1309484 "Recruitment and activation of Chk1"
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| xref | Reactome:1309486 "Stalling of DNA replication fork and RPA binding"
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| xref | Reactome:1309488 "Binding of ATR-ATRIP to the RPA-ssDNA complex"
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| xref | Reactome:1309505 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:1309514 "Activation of claspin"
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| xref | Reactome:1309515 "Loading of claspin onto DNA during replication origin firing"
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| xref | Reactome:1326412 "Activation of ATR in response to replication stress"
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| xref | Reactome:1336412 "Recruitment of Rad17-RFC complex to DNA"
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| xref | Reactome:1336424 "Recruitment and activation of Chk1"
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| xref | Reactome:1336426 "Stalling of DNA replication fork and RPA binding"
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| xref | Reactome:1336428 "Binding of ATR-ATRIP to the RPA-ssDNA complex"
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| xref | Reactome:1336448 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:1336464 "Activation of claspin"
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| xref | Reactome:1336465 "Loading of claspin onto DNA during replication origin firing"
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| xref | Reactome:1352528 "Activation of ATR in response to replication stress"
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| xref | Reactome:1360397 "Recruitment of Rad17-RFC complex to DNA"
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| xref | Reactome:1360406 "Recruitment and activation of Chk1"
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| xref | Reactome:1360408 "Stalling of DNA replication fork and RPA binding"
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| xref | Reactome:1360410 "Binding of ATR-ATRIP to the RPA-ssDNA complex"
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| xref | Reactome:1360419 "Activation of claspin"
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| xref | Reactome:1360420 "Loading of claspin onto DNA during replication origin firing"
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| xref | Reactome:1372756 "Activation of ATR in response to replication stress"
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| xref | Reactome:1381179 "Recruitment of Rad17-RFC complex to DNA"
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| xref | Reactome:1381192 "Recruitment and activation of Chk1"
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| xref | Reactome:1381194 "Stalling of DNA replication fork and RPA binding"
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| xref | Reactome:1381196 "Binding of ATR-ATRIP to the RPA-ssDNA complex"
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| xref | Reactome:1381209 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:1381226 "Activation of claspin"
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| xref | Reactome:1381227 "Loading of claspin onto DNA during replication origin firing"
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| xref | Reactome:1392766 "Activation of ATR in response to replication stress"
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| xref | Reactome:1402472 "Recruitment of Rad17-RFC complex to DNA"
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| xref | Reactome:1402481 "Recruitment and activation of Chk1"
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| xref | Reactome:1402483 "Stalling of DNA replication fork and RPA binding"
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| xref | Reactome:1402485 "Binding of ATR-ATRIP to the RPA-ssDNA complex"
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| xref | Reactome:1402506 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:1402515 "Activation of claspin"
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| xref | Reactome:1402516 "Loading of claspin onto DNA during replication origin firing"
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| xref | Reactome:1417243 "Activation of ATR in response to replication stress"
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| xref | Reactome:1430527 "Recruitment of Rad17-RFC complex to DNA"
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| xref | Reactome:1430539 "Recruitment and activation of Chk1"
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| xref | Reactome:1430541 "Stalling of DNA replication fork and RPA binding"
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| xref | Reactome:1430543 "Binding of ATR-ATRIP to the RPA-ssDNA complex"
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| xref | Reactome:1430566 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:1430575 "Activation of claspin"
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| xref | Reactome:1430576 "Loading of claspin onto DNA during replication origin firing"
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| xref | Reactome:1450331 "Activation of ATR in response to replication stress"
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| xref | Reactome:1459113 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:1459123 "Loading of claspin onto DNA during replication origin firing"
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| xref | Reactome:1470872 "Activation of ATR in response to replication stress"
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| xref | Reactome:1476624 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:1483226 "Activation of ATR in response to replication stress"
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| xref | Reactome:1518138 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:1521172 "Activation of ATR in response to replication stress"
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| xref | Reactome:1530550 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:1532653 "Activation of ATR in response to replication stress"
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| xref | Reactome:176101 "Recruitment of Rad17-RFC complex to DNA"
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| xref | Reactome:176116 "Recruitment and activation of Chk1"
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| xref | Reactome:176175 "Stalling of DNA replication fork and RPA binding"
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| xref | Reactome:176187 "Activation of ATR in response to replication stress"
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| xref | Reactome:176250 "Binding of ATR-ATRIP to the RPA-ssDNA complex"
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| xref | Reactome:176264 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
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| xref | Reactome:176298 "Activation of claspin"
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| xref | Reactome:176318 "Loading of claspin onto DNA during replication origin firing"
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| xref | Wikipedia:DNA_replication
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| is_a | GO:0006259 ! DNA metabolic process
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| is_a | GO:0034645 ! cellular macromolecule biosynthetic process
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| relationship | has_part GO:0071897 ! DNA biosynthetic process
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